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Nexium can be prescribed to prevent and treat peptic ulcers that occur as a side effect of non-steroidal anti-inflammatory drugs prescribed to treat arthritis, for example diclofenac.
Nexium is prescribed in combination with antibiotics to eradicate Helicobacter pylori from the gut. The esomeprazole creates an environment in the gut in which the antibiotics can work effectively against the H pylori bacteria. The reduced acid in the gut allows the ulcer to heal, and both actions help prevent the ulcer from recurring.
Nexium is prescribed to treat ulcers in the stomach or upper intestine that are associated with a type of bacteria called Helicobacter pylori. This type of bacteria is the most common cause of peptic ulcers. The bacteria cause the stomach to produce too much acid, which irritates the lining of the stomach and upper intestine and causes ulcers.
Nexium reduces the production of stomach acid and thus reduces acid flowing back into the foodpipe. It is prescribed to relieve the symptoms of gastro-oesophageal reflux disease, such as heartburn. It is prescribed to treat reflux oesophagitis, because stopping the acid flowing back into the foodpipe allows the lining of the foodpipe to heal. Esomeprazole is prescribed for the long-term management of people with healed oesophagitis, as suppressing the production of stomach acid helps prevent this condition recurring.
Nexium relieves heartburn and other symptoms caused by the backflow of stomach acid into the canal to the stomach (the esophagus)--a condition known as gastroesophageal reflux disease. It is prescribed to heal the damage (erosive esophagitis) that reflux disease can cause.
Nexium tablets and injection contain the active ingredient esomeprazole, which is a type of drug called a proton pump inhibitor. It acts in the stomach to decrease the production of stomach acid.
Acid is produced in the stomach as a normal part of the digestive process. However, in the condition known as gastro-oesophageal reflux disease or acid reflux, this acid is allowed to flow back into the food pipe, where it causes pain and a burning sensation known as heartburn. The acid can irritate and cause inflammation of the lining of the foodpipe.
Indicated in combination with the antibiotics Biaxin and Amoxil, Nexium is prescribed to treat the infection that causes most duodenal ulcers (ulcers occurring just beyond the exit from the stomach).
Like its sister drug Prilosec, Nexium works by reducing the production of stomach acid.
Proton pumps are found on cells that line the stomach and are prescribed by these cells to produce stomach acid. Esomeprazole works by inhibiting the action of the proton pumps, and this reduces the production of stomach acid.
Nexium is prescribed for the treatment of:
- Treatment and prevention of peptic ulcers associated with non-steroidal anti-inflammatory drugs;
- Gastro-oesophageal reflux disease;
- Eradicating helicobacter pylori bacteria from the gut, which helps peptic ulcers to heal and prevents them from recurring;
Nexium Side Effects
Nexium side effects that you should report to your health care professional or doctor as soon as possible:
- Blurred vision;
- Difficulty sleeping;
- Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain;
- Dry mouth;
- Excess gas in the stomach and intestines;
- Hair loss;
- Increased sweating;
- Inflammation of the skin;
- Liver or blood disorders;
- Pain in the muscles and joints;
- Pins and needles;
- Skin reactions such as rash and itch;
- Swelling of the legs and ankles due to excess fluid retention;
- Taste disturbance;
- Abdominal pain;
Gastroesophageal Reflux Disease (GERD)
For relief of symptoms, the usual dosage is one 20-mg capsule daily for 4 weeks.
If symptoms persist, your doctor may prescribe an additional 4 weeks of therapy.
If you have severe liver problems, you should take no more than 20 mg of Nexium per day.
As part of a three-drug treatment to rid the body of ulcer-causing H. Pylori bacteria, Nexium is prescribed at a dosage of 40 mg once daily for 10 days.
To heal damage, the dosage is 20 or 40 mg of Nexium once daily for 4 to 8 weeks.
To maintain healing, the dosage is 20 mg once daily.
If you haven't fully healed after 8 weeks, your doctor may prescribe an additional 4 to 8 weeks of therapy.