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An allergic reaction to this drug is possible and may occur without warning.
Breathing disorders have occurred in people taking nitrofurantoin.
However, all these reactions occur rarely and generally in those receiving nitrofurantoin therapy for 6 months or longer.
It has been known to cause pulmonary fibrosis (an abnormal increase in fibrous tissue of the lungs).
Nitrofurantoin, an antibacterial drug, is prescribed for the treatment of urinary tract infections caused by certain strains of bacteria.
Sudden and severe lung reactions are characterized by fever, chills, cough, chest pain, and difficulty breathing.
Symptoms include a feeling of ill health and a persistent cough.
The drug can cause inflammation of the lungs marked by coughing, difficulty breathing, and wheezing.
These acute reactions usually occur within the first week of treatment and subside when therapy with nitrofurantoin is stopped.
This condition can develop gradually without symptoms and can be fatal.
Your doctor should monitor your condition closely, especially if you are receiving long-term treatment with this medication.
Furadantin Side Effects
Furadantin side effects that you should report to your health care professional or doctor as soon as possible:
More common side effects may include:
- Lack or loss of appetite;
Less common or rare side effects may include:
- Yellowing of the skin and whites of the eyes;
- Skin swelling or welts;
- Skin inflammation with flaking;
- Severe allergic reactions;
- Psychotic reactions;
- Peeling skin;
- Or muscle weakness;
- Muscle pain;
- Joint pain;
- Itchy red skin patches;
- Irregular heartbeat;
- Involuntary eye movement;
- Intestinal inflammation;
- Inflammation of the nerves causing symptoms of numbness;
- Hair loss;
- Eye disorder;
- Exaggerated sense of well-being;
- Difficulty breathing;
- Chest pain;
- Blue skin;
- Abdominal pain/discomfort;
Furadantin is contraindicated if you have any of the following conditions:
- If you are receiving long-term treatment with this drug;
- If you are sensitive to or have ever had an allergic reaction to nitrofurantoin or other drugs of this type, such as furoxone;
- If you develop symptoms such as muscle weakness or lack of sensation;
- If you experience diarrhea;
- If you have any unusual symptoms while you are taking this drug;
- If you have poor kidneys, producing little or no urine;
Do not take Furadantin with any of the following drugs:
- The gout drugs probenecid and sulfinpyrazone and other drugs that increase the amount of uric acid in the urine;
- Magnesium trisilicate (gaviscon antacid tablets);
For long-term treatment, your doctor may reduce your dosage to 50 to 100 milligrams taken at bedtime.
The recommended dosage of Macrodantin is 50 to 100 milligrams taken 4 times a day.
The recommended dosage of Macrobid is one 100 milligram capsule every 12 hours for 7 days.
The drug is more likely to cause lung and liver problems in members of this group and because more older adults have poor kidneys, the risk of toxic reactions to Macrodantin is greater.
Doctors tend to prescribe lower doses of Macrodantin for older adults.
This medication should not be prescribed for children under 1 month of age.
For the long-term treatment of children, the doctor may prescribe daily doses as low as 1 milligram per 2.2 pounds of body weight taken in 1 or 2 doses per day.
The recommended daily dosage of Macrodantin for infants and children over 1 month of age is 5 to 7 milligrams per 2.2 pounds of body weight, divided into 4 doses over 24 hours.
The dosage of Macrobid for children over 12 years of age is one 100 milligram capsule every 12 hours for 7 days. Safety and effectiveness have not been established for children under 12.
An overdose of nitrofurantoin does not cause any specific symptoms other than vomiting.
If vomiting does not occur soon after an excessive dose, it should be induced.