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Exelon is prescribed in the treatment of mild to moderate Alzheimer's disease. Alzheimer's disease causes physical changes
in the brain that disrupt the flow of information and interfere with memory, thinking, and behavior. By boosting levels of the
chemical messenger acetylcholine, Exelon can temporarily improve brain function in some Alzheimer's sufferers, though it does
not halt the progress of the underlying disease. Exelon may become less effective as the disease progresses.
Exelon capsules and oral solution both contain the active ingredient rivastigmine, which is a type of drug called an
acetylcholinesterase inhibitor. It works by slowing the breakdown of a compound in the brain called acetylcholine.
Acetylcholine is a natural compound known as a neurotransmitter. Neurotransmitters are stored in nerve cells in the brain
and nervous system, and are involved in transmitting messages between the nerve cells. They are necessary for the normal
functioning of the brain and nervous system. Acetylcholine in the brain is continually being released by nerve cells, and then
broken down by another natural chemical called acetylcholinesterase.
One of the features of both Alzheimer's disease and Parkinson's disease appears to be a lower than normal level of
acetylcholine in the brain. This is due in part to degeneration of brain cells, in particular those that normally release
Rivastigmine increases the level of acetylcholine in the brain. It does this by preventing the action of
acetylcholinesterase, the compound which normally breaks it down. This slows the breakdown of acetylcholine that is released
from remaining undamaged nerve cells in the brain.
The result of this is increased activity of acetylcholine in the brain. This improves the cognitive processes of thinking,
learning and memory, and improves the symptoms of dementia and daily functioning in Alzheimer's disease.
Rivastigmine is prescribed to treat mild to moderately severe dementia in people with Alzheimer's disease or Parkinson's
disease. However, it only slows the worsening of the dementia, rather than being a cure. If the drug has not slowed the
worsening of symptoms after three months of treatment at the maintenance dose, it should be stopped. For patients who continue
treatment, the benefit of the drug should be reassessed on a regular basis and stopped when it is considered that the drug is
no longer providing a beneficial effect.
Why is Exelon bought?
- worsening of parkinson's symptoms;
- weakness or loss of strength;
- ulceration of the stomach or intestine;
- shaking usually of the hands;
- mild to moderately severe dementia in people with parkinson's disease;
- mild to moderately severe alzheimer's dementia;
- increased sweating;
- false perceptions of things that are not really there;
- disturbances of the gut such as nausea vomiting diarrhoea indigestion or abdominal pain;
- difficulty in sleeping;
- decreased appetite and weight loss;
- chest pain;
- abnormal heart beats;
Exelon Side Effects
Exelon side effects that you should report to your health care professional or doctor as soon as possible:
- weight loss;
- urinary infection;
- unwell feeling;
- loss of appetite;
- inflamed nasal passages;
- increased sweating;
- high blood pressure;
- flu-like symptoms;
- accidental injury;
- abdominal pain;
The usual starting dose is 1.5 mg 2 times a day for at least 2 weeks. At 2 week intervals, the doctor may then increase the dose to 3 mg, 4.5 mg, and finally 6.0 mg 2 times a day. Higher doses tend to be more effective. The maximum dosage is 12 mg daily.
If side effects such as nausea and vomiting begin to develop, the doctor may recommend skipping a few doses, then starting again at the same or the next lowest dosage.